Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1-alkyl- > 1-alkenyl-LPA.
Pathway
Class A/1 (Rhodopsin-like receptors); GPCR downstream signaling; GPCRs, Class A Rhodopsin-like; LPA receptor mediated events
Citations
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