Lansau is a traditional medicine of Muna ethnic which comprised of 44 kinds of plants that was inherited and believed to have a restorative power in healing kinds of diseases that are consumed based on the trust and the philosophy values by Muna ethnic. This study aimed to find out the characteristic of pharmacognistic on traditional plats of lansau comprised of determination of the plants, the experiment on macroscopic (experiments on organoleptic, the observation to the characteristic of morphology) and the experiment on microscopic. The sample of this study was the plant of lansau consisted of: bhangkudu, kamena-mena, patirangka, soni, katapi, ghontoghe, Libbho, kaghai-ghai, lansale, daru, sirikaya, Sandana, Katabatabako,Sambiloto,Kambhadawa,Lakoora, Kerseni, Kusambi, Bhea, Dana,Radhawali, Katimboka, Wonta, Bandara, Bumalaka, Kulidawa, Gondu, Patiwala ngkadea, Komba-komba, Ladha, Tongkoea, Kaghuse-ghuse, Kumbou,Kaembu-embu, Rogili, Rogo, Kalamandinga, Kula, Ntanga-Ntanga, Padamalala, Kumis Kucing, Kabote-Bote, Tulasi dan Kasape. The sample was obtained in the District of Bata Laiworu the Regency of Muna Province of southeast Sulawesi. The determination result which was conducted in LIPI Bogorwas gained datas of name of plants from 44 of the medicine used in the extraction of lansau. Result of macroscopic experiment on color, odor, taste and size of the plants was different from the outcome of plants microscopic which has the type of stomata, trichomes, and the concentrate of different vessel.