Recombinant fragment, corresponding to a region within amino acids 473-730 of Human EPLIN (UniProt Q9UHB6).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/3000; ICC/IF: 1/100 - 1/1000;
Target
Alternative Names
LIMA1; LIM domain and actin binding 1; EPLIN; SREBP3; LIM domain and actin-binding protein 1; 1110021C24Rik; epithelial protein lost in neoplasm beta; sterol regulatory element binding protein 3;
Binds to actin monomers and filaments. Increases the number and size of actin stress fibers and inhibits membrane ruffling. Inhibits actin filament depolymerization. Bundles actin filaments, delays filament nucleation and reduces formation of branched filaments.
Pathway
Stabilization and expansion of the E-cadherin adherens junction;
Citations
Publication ()
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COA
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