Anti-LILRA2 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human LILRA2 is used for rabbit immunization.

Conjugate

Alternative Names

LILRA2; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2; leukocyte immunoglobulin-like receptor subfamily A member 2; CD85h; ILT1; LIR 7; LIR7; ILT-1; immunoglobulin-like transcript 1; CD85 antigen-like family member H; leuk

Entrez Gene ID

UniProt ID

Antigen Description

Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor.

Pathway

Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem;