Recombinant full length protein corresponding to Human LETMD1 aa 1-360.Sequence: MALSRVCWARSAVWGSAVTPGHFVTRRLQLGRSGLAWGAPRSSKLHLSPK ADVKNLMSYVVTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADA KKARRIKTNMWKHNIKFHQLPYREMEHLRQFRQDVTKCLFLGIISIPPFA NYLVFLLMYLFPRQLLIRHFW
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/2000; IHC-P: 1/50 - 1/200.
Target
Alternative Names
LETMD1; LETM1 domain containing 1; LETM1 domain-containing protein 1; cervical cancer 1 protooncogene; HCCR1; regulator of TP53; cervical cancer proto-oncogene 2 protein; cervical cancer 1 proto-oncogene protein p40; HCCR-1; HCCR-2; HCRR-2; 1110019O13Rik;
LETMD1 is involved in tumorigenesis and may function as a negative regulator of the TP53/p53. It is found in kidney, liver, skeletal muscle, heart and brain and is over-expressed in various tumors including leukemia, lymphoma, and carcinomas of the breast, kidney, ovary, stomach, colon and uterine cervix. There are six isoforms.
Citations
Publication ()
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