Synthetic peptide corresponding to a region within internal sequence amino acids 216-265 (YPNSIQEYIR QLPPNFPYRD DVMSVNPTCL VLIILLFISI ILTFKGYLIS) of human LAPTM4B (NP_060877).
Conjugate
Unconjugated
Applications
Application Notes
ICC/IF: 5 μg/ml; IHC-P: 1/100; WB: 1 μg/ml;
Target
Alternative Names
LAPTM4B; lysosomal protein transmembrane 4 beta; LC27; LAPTM4beta; lysosomal-associated transmembrane protein 4B; lysosome-associated transmembrane protein 4-beta; lysosomal associated protein transmembrane 4 beta;
LAPTM4B belongs to the LAPTM4/LAPTM5 transporter family. It has an active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.
Pathway
Lysosome;
Citations
Publication ()
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COA
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