K6HF (NP_004684, 141 a.a. ~ 240 a.a) partial recombinant protein with GST tag. The sequence is TIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLF DSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYE
Conjugate
Unconjugated
Target
Alternative Names
KRT75; keratin 75; PFB; K6HF; KB18; keratin, type II cytoskeletal 75; K75; CK-75; hK6hf; keratin-75; cytokeratin-75; type II keratin-18; cytokeratin type II; type II keratin-K6hf; type-II keratin Kb18; keratin-6 hair follicle;
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. This gene is expressed in the companion layer, upper germinative matrix region of the hair follicle, and medulla of the hair shaft. The encoded protein plays an essential role in hair and nail formation. Variations in this gene have been associated with the hair disorders pseudofolliculitis barbae (PFB) and loose anagen hair syndrome (LAHS).
Citations
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