Anti-KRT33B (aa 140-404) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant fragment, corresponding to a region within amino acids 140-404 of Human KRTHA3B (Uniprot ID: Q14525)

Conjugate

Application Notes

WB: 1/5000 - 1/20000; IHC-P: 1/100 - 1/1000; ICC/IF: 1/100 - 1/1000;

Alternative Names

KRT33B; keratin 33B; K33B; HA3II; Ha-3II; KRTHA3A; KRTHA3B; hHa3-II; keratin, type I cuticular Ha3-II; type I hair keratin 3B; hard keratin, type I, 3II; keratin, hair, acidic, 3B; hair keratin, type I Ha3-II;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex.