A synthetic peptide of human KLRC4 is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
KLRC4; killer cell lectin-like receptor subfamily C, member 4; NKG2-F type II integral membrane protein; NKG2 F; NK cell receptor F; natual killer cell group 2-F; NKG2-F-activating NK receptor; NKG2F; NKG2-F; FLJ17759; FLJ78582;
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC4 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. The 3 end of the KLRC4 transcript includes the first non-coding exon found at the 5 end of the adjacent D12S2489E gene transcript.
Pathway
Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem.
Citations
Publication ()
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