KLRB1 (NP_002249, 126 a.a. ~ 225 a.a) partial recombinant protein with GST tag. The sequence is ESSLLLIRDKDELIHTQNLIRDKAILFWIGLNFSLSEKNWKWINGSFLNSNDLEIRGDAK ENSCISISQTSVYSEYCSTEIRWICQKELTPVRNKVYPDS
Conjugate
Unconjugated
Target
Alternative Names
KLRB1; killer cell lectin-like receptor subfamily B, member 1; NKR; CD161; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A; killer cell lectin-like receptor subfamily B member 1; C-type lectin domain family 5 member B; natural killer cell surface protein P1A;
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus.
Pathway
Malaria.
Citations
Publication ()
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