Mouse anti-Human KLK8 polyclonal antibody

Species Reactivity

Human

Immunogen

KLK8 (NP_009127, 97 a.a. ~ 204 a.a) partial recombinant protein with GST tag. The sequence is EIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSG WGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKG

Conjugate

Alternative Names

KLK8; kallikrein-related peptidase 8; NP; HNP; NRPN; PRSS19; TADG14; kallikrein-8; ovasin; serine protease 19; serine protease TADG-14; tumor-associated differentially expressed gene 14 protein;

Entrez Gene ID

UniProt ID

Antigen Description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

Pathway

Spinal Cord Injury;