Anti-KLHDC3 (full length) polyclonal antibody

Species Reactivity

Human

Immunogen

KLHDC3 (AAH45612, 1 a.a. ~ 266 a.a) full-length recombinant protein with GST tag. The sequence is MDTQPSSSTTQSSFGAGGMTPKGPAMCSMPLTSADCFSNDIHKLDTSTMTWTLICTKGSP ARWRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTPVLP EGRRSHSAFGYNGELYIFGGYNARLNWHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCC CIVGDKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSPSLKTLCKLAVIQYNLDQSCL PHDIRWELNAMTTNSNISRPIVSSHG

Conjugate

Alternative Names

KLHDC3; kelch domain containing 3; PEAS; dJ20C7.3; kelch domain-containing protein 3; testis intracellular mediator protein;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2, a protein involved in the activation of the V(D)J recombination. In mouse, this gene is found to be expressed specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasma and meiotic chromatin, suggesting that this gene may be involved in meiotic recombination.

Pathway

IRE1alpha activates chaperones; Unfolded Protein Response (UPR);