Anti-KLF8 polyclonal antibody

Species Reactivity

Human

Immunogen

A synthetic peptide corresponding to human KLF8. The sequence is VDMDKLINNLEVQ-C

Conjugate

Application Notes

ELISA: 1:32000; WB: 1-3 μg/mL. & The optimal working dilution should be determined by the end user.

Alternative Names

KLF8; Kruppel-like factor 8; BKLF3; ZNF741; Krueppel-like factor 8; zinc finger protein 741; basic kruppel-like factor 3; basic krueppel-like factor 3;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants.

Pathway

Signaling events mediated by focal adhesion kinase;