Two co(ii)-Containing coordination polymers: Catalytic dye degradation and anti-cancer activity on the colon cancer cells by regulating the intestinal butyrate production and HDAC2 expression
JOURNAL OF MOLECULAR STRUCTURE
Authors: Wang, Teng; Ling, Xiao; Guo, Shuang; Guo, Jian-Qiang
Abstract
Through utilizing a mixed-ligand method, two novel coordination polymers (CPs) containing Co(II) of [Co(L)(dcdps)](n) (1) and {Co(L)(bdc)}(n) (2) [H(2)bdc = 1,4-dicarboxybenzene; H(2)dcdps = 4,4'-sulfonyldibenzoic acid and L = 4,4'-(2,5-bis(methylthio)-1,4-phenylene)dipyridine] have been prepared by the solvothermal method through Co(NO3)(2)center dot 6H(2)O reacting with the methylthio functionalized dipyridine ligand L in the existence of distinct carboxylic ligands. Compound 2 contains excellent water stability can effectively degrade the methylene blue in the water solution under the irradiation of ultraviolet, which is expected to become a potential photo active material. Furthermore, the inhibitory effect of compound against the production of intestinal butyrate, as well as the HDAC2 expression in colon cancer cells was evaluated. The ELISA test kit was conducted to detect the butyrate content in the intestinal tissue. The real time RT-PCR method was implemented, and the HDAC2 gene relative expression levels in colon cells was measured. Finally, our aim is to generate novel mechanism for the treatment of anti-colon cancer. (C) 2020 Elsevier B.V. All rights reserved.
Automation Kit for Dual-Mode Military Unmanned Ground Vehicle for Surveillance Missions
IEEE INTELLIGENT TRANSPORTATION SYSTEMS MAGAZINE
Authors: Naranjo, Jose E.; Jimenez, Felipe; Anguita, Manuel; Rivera, Jose Luis
Abstract
The field of autonomous vehicles is an area of great importance nowadays among Intelligent Transport Systems. These autonomous vehicles must meet high standards of robustness, safety and protection to make autonomous driving safer than human driving, thus improving current accident rates and energy efficiency, so its complete implementation in the market is expected in the long term. However, there are other areas, such as the agricultural and military sectors, where the demand for technologies related to autonomous driving is also high but the applicability could be faster. In this sense, the unmanned ground military vehicles (UGV) are a technology available in international armies for some years, but that is still subject to a series of technical, logistical and material limitations that reduce its applicability. This paper presents an automation kit for transforming military service vehicles into military UGVs, developed through the transfer of autonomous vehicle technology from the civil sector to the military sector. This kit has been installed in a quite common vehicle of the Spanish army, in order to provide two functional capabilities: autonomous navigation and teleoperation, in off-road environments with minimal or no traffic marks or infrastructure aids. The vehicle equipped with this kit is oriented to different missions such as circulation in convoys, operation as tele-operated probe vehicle and perimeter surveillance. The automation kit involves no permanent modifications in the vehicle that can be driven manually when desired, allows vehicles to be used both in missions in conflict zones and to support operations in emergencies and natural catastrophes, and can be easily installed in any kind of vehicle.