Fusion protein corresponding to residues near the C terminal of human kin of IRRE like 2 (Drosophila)
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:200-1:1000
General Notes
This product (Catalog No. DPABH-29249) is a rabbit-derived IgG polyclonal antibody raised against human KIRREL2. It has been affinity purified by protein A. This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. DPABH-29249 is suitable for use in Western blot (WB) (1:200–1:1,000) application. DPABH-29249 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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