Recombinant human KIR3DL1 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 22-344 aa of BC028206
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:1000
General Notes
This product (Catalog No. DPABH-09473) is a rabbit-derived polyclonal antibody raised against human KIR3DL1, targeting the amino acid region 22–344 of the protein. It has been affinity purified by Protein A. Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR3DL1 is a receptor on natural killer (NK) cells for HLA Bw4 allele. It inhibits the activity of NK cells thus preventing cell lysis. KIR3DL1 and KIR3DS1 are highly homologous. DPABH-09473 is suitable for use in Western blot (WB) (1:500–1:1,000) application. DPABH-09473 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
KIR3DL1; CD158 antigen-like family member E; CD158E; CD158E1; HLA-BW4-specific inhibitory NK cell receptor
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