Recombinant fusion protein of human KIAA0196 (NP_055661.3).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:2000-1:5000 IHC: 1:50-1:200
General Notes
This product (Catalog No. DPABH-22513) is a rabbit-derived polyclonal antibody raised against human KIAA0196. This antibody exhibits cross-reactivity with KIAA0196 from mouse and rat. It has been affinity purified by Protein A. This gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin-repeat-containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive, lower extremity spasticity caused by axonal degeneration in the terminal portions of the longest descending and ascending corticospinal tracts. More than 30 loci (SPG1-33) have been implicated in hereditary spastic paraplegia diseases. DPABH-22513 is suitable for use in Western blot (WB) (1:2,000–1:5,000), IHC (1:50–1:200) applications. DPABH-22513 is supplied as a liquid formulation in PBS with 0.02% sodium azide, 50% glycerol, pH7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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