Anti-KDM2B (aa 457-555) polyclonal antibody

Species Reactivity

Human

Immunogen

FBXL10 (NP_115979, 457 a.a. ~ 555 a.a) partial recombinant protein with GST tag. The sequence is LGKKPKAPALRFLKRTLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKG LKALVEKLESLPENKKCVPEGIEDPQALLEGVKNVLKEH

Conjugate

Alternative Names

KDM2B; lysine (K)-specific demethylase 2B; CXXC2; Fbl10; PCCX2; FBXL10; JHDM1B; lysine-specific demethylase 2B; F-box protein FBL10; F-box/LRR-repeat protein 10; CXXC-type zinc finger protein 2; protein-containing CXXC domain 2; [Histone-H3]-lysine-36 dem

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.