Specifications
Immunogen
A synthetic peptide of human KCNJ6 is used for rabbit immunization.
Target
Alternative Names
KCNJ6; potassium inwardly-rectifying channel, subfamily J, member 6; KCNJ7; G protein-activated inward rectifier potassium channel 2; BIR1; GIRK2; hiGIRK2; KATP2; Kir3.2; inward rectifier K(+) channel Kir3.2; inward rectifier potassium channel KIR3.2; pot
Product Background
Antigen Description
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.
Pathway
Activation of G protein gated Potassium channels, organism-specific biosystem; Activation of GABAB receptors, organism-specific biosystem; Cholinergic synapse, organism-specific biosystem; Dopaminergic synapse, organism-specific biosystem; Dopaminergic synapse, conserved biosystem; G protein gated Potassium channels, organism-specific biosystem; GABA B receptor activation, organism-specific biosystem.
Citations
Publication ()
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