Specifications
Immunogen
A synthetic peptide of human KCNH4 is used for rabbit immunization.
Target
Alternative Names
KCNH4; potassium voltage-gated channel, subfamily H (eag-related), member 4; potassium voltage-gated channel subfamily H member 4; elk1; Kv12.3; ELK channel 1; brain-specific eag-like channel 2; ether-a-go-go-like potassium channel 1; ether-a-go-go K(+) c
Product Background
Antigen Description
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system.
Pathway
Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Voltage gated Potassium channels, organism-specific biosystem;
Citations
Publication ()
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