Anti-KCND1 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human KCND1 is used for rabbit immunization.

Conjugate

Alternative Names

KCND1; potassium voltage-gated channel, Shal-related subfamily, member 1; potassium voltage-gated channel subfamily D member 1; Kv4.1; shal-type potassium channel; voltage-gated potassium channel Kv4.1; voltage-gated potassium channel subunit Kv4.1; KV4.1

Entrez Gene ID

UniProt ID

Antigen Description

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This gene is expressed at moderate levels in all tissues analyzed, with lower levels in skeletal muscle.

Pathway

Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Voltage gated Potassium channels, organism-specific biosystem;