Anti-KCNAB2 monoclonal antibody, clone T28-81

Antibody Isotype

IgG1

Clone

T28-81

Species Reactivity

Mouse; Rat; Human; Zebrafish

Immunogen

Fusion protein of full length Rat Kv beta 2

Conjugate

Application Notes

ICC: 0.1 - 1 μg/ml; ICC/IF: 1 - 10 μg/ml; WB: 1 μg/ml; IHC-P: 0.1 - 1 μg/ml; IHC-Fr: 0.1 - 1 μg/ml.

Alternative Names

KCNAB2; potassium voltage-gated channel, shaker-related subfamily, beta member 2; voltage-gated potassium channel subunit beta-2; kv-beta-2; K(+) channel subunit beta-2; potassium voltage gated channel, shaker related subfamily, beta member 2;

Entrez Gene ID

UniProt ID

Antigen Description

Voltage gated potassium (Kv) channels represent the most complex class of voltage gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence related potassium channel genes: shaker, shaw, shab, and shal, have been identified in Drosophila, and each has been shown to have human homolog(s). This protein belongs to the potassium channel, voltage gated, shaker related subfamily and is one of the beta subunits, which are auxiliary proteins associating with functional Kv alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.