Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles. Isoform 1 could be involved in brain-specific synaptic vesicle recycling. Inhibits ARHGAP31 activity toward RAC1.
Pathway
Cell death signalling via NRAGE, NRIF and NADE; G alpha (12/13) signalling events; Internalization of ErbB1; Regulation of CDC42 activity
Citations
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Q: What experiments can DPABH-07873 antibodies be used for?
A: WB
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