Specifications
Immunogen
A synthetic peptide corresponding to human ITPR3. The sequence is C-DKKERPTDEEGFLH
Applications
Application Notes
ELISA: 1:128000. & The optimal working dilution should be determined by the end user.
Target
Alternative Names
ITPR3; inositol 1,4,5-trisphosphate receptor, type 3; IP3R; IP3R3; inositol 1,4,5-trisphosphate receptor type 3; insP3R3; IP3 receptor; type 3 InsP3 receptor; inositol 1,4,5-triphosphate receptor, type 3;
Product Background
Antigen Description
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.
Pathway
Adaptive Immune System; Alzheimers Disease; Ca2+ pathway; Calcium signaling pathway.
Citations
Publication ()
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COA
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