Specifications
Immunogen
ITPR1 (NP_002213, 2470 a.a. ~ 2577 a.a) partial recombinant protein with GST tag. The sequence is EHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNL IFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHI
Target
Alternative Names
ITPR1; inositol 1,4,5-trisphosphate receptor, type 1; ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94; inositol 1,4,5-trisphosphate receptor type 1; IP3R 1; IP3 receptor; type 1 InsP3 receptor; inositol 1,4,5-triphosphate receptor, type 1; p
Product Background
Antigen Description
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.
Pathway
Adaptive Immune System; Alzheimers Disease; B Cell Receptor Signaling Pathway; Calcium Regulation in the Cardiac Cell
Citations
Publication ()
Have you cited DPAB-DC1752 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
