Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Iroquois homeobox protein 3 aa 50-150 (Cysteine residue). The exact sequence is proprietary.Database link: P78415
Conjugate
Unconjugated
Applications
Application Notes
Flow Cyt: 1/10 - 1/100; WB: 1/1000 - 1/10000.
Target
Alternative Names
IRX3; iroquois homeobox 3; iroquois-class homeodomain protein IRX-3; IRX 1; homeodomain protein IRXB1; iroquois homeobox protein 3; iroquois-class homeodomain protein IRX-1; IRX-1; IRXB1; FLJ99187;
Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells.
Citations
Publication ()
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