General Notes
This product (Catalog No. DPABH-27733) is a rabbit-derived IgG polyclonal antibody raised against human IRAK1BP1. This antibody exhibits cross-reactivity with IRAK1BP1 from mouse. It has been affinity purified by protein A. IRAK1BP1 (Interleukin-1 receptor-associated kinase 1-binding protein 1), also known as SIMPL, is a protein-coding gene that acts as a key regulator of innate immune responses by modulating NF-κB signaling. It functions as a molecular switch, often reducing proinflammatory cytokine production by promoting anti-inflammatory p50/p50 homodimer translocation, aiding in the development of endotoxin (LPS) tolerance.
DPABH-27733 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:50–1:200) applications.
DPABH-27733 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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