Specifications
Immunogen
PIB5PA (NP_055237, 361 a.a. ~ 470 a.a) partial recombinant protein with GST tag. The sequence is FLLQFAFRDDMPLVRLEVADEWVRPEQAVVRYRMETVFARSSWDWIGLYRVGFRHCKDYV AYVWAKHEDVDGNTYQVTFSEESLPKGHGDFILGYYSHNHSILIGITEPF
Target
Alternative Names
INPP5J; inositol polyphosphate-5-phosphatase J; PIPP; INPP5; PIB5PA; phosphatidylinositol 4,5-bisphosphate 5-phosphatase A; inositol polyphosphate 5-phosphatase J; phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A;
Product Background
Antigen Description
INPP5J (inositol polyphosphate-5-phosphatase J) is a protein-coding gene. Diseases associated with INPP5J include oculocerebrorenal syndrome, and glanders, and among its related super-pathways are D-myo-inositol (1,3,4)-trisphosphate biosynthesis and Phosphatidylinositol signaling system. GO annotations related to this gene include SH3 domain binding and inositol-1,4,5-trisphosphate 5-phosphatase activity. An important paralog of this gene is INPP5B.
Pathway
1D-myo-inositol hexakisphosphate biosynthesis II (mammalian); 3-phosphoinositide degradation; D-myo-inositol (1,3,4)-trisphosphate biosynthesis; D-myo-inositol (1,4,5)-trisphosphate degradation.
Citations
Publication ()
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