Specifications
Immunogen
Recombinant fragment, corresponding to a region within amino acids 591-857 of the Human INPP5F protein (Q01968).
Applications
Application Notes
WB: 1/500 - 1/3000; IHC-P: 1/100 - 1/500; ICC/IF: 1/100 - 1/500.
Target
Alternative Names
INPP5F; inositol polyphosphate-5-phosphatase F; phosphatidylinositide phosphatase SAC2; hSac2; KIAA0966; SAC2; Sac domain-containing inositol phosphatase 2; sac domain-containing phosphoinositide 5-phosphatase 2; hSAC2; MSTP007; MSTPO47; FLJ13081; MGC5977
Product Background
Antigen Description
Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate. May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes.
Pathway
3-phosphoinositide degradation; D-myo-inositol (1,4,5)-trisphosphate degradation; superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism;
Citations
Publication ()
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COA
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