Anti-INMT (aa 174-263) polyclonal antibody

Species Reactivity

Human

Immunogen

INMT (NP_006765, 174 a.a. ~ 263 a.a) partial recombinant protein with GST tag. The sequence is DAYRAALCNLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKGEVEQAVLDAGFDIE QLLHSPQSYSVTNAANNGVCCIVARKKPGP

Conjugate

Alternative Names

INMT; indolethylamine N-methyltransferase; TEMT; amine N-methyltransferase; nicotine N-methyltransferase; arylamine N-methyltransferase; thioether S-methyltransferase; indolamine N-methyltransferase; aromatic alkylamine N-methyltransferase;

Entrez Gene ID

UniProt ID

Antigen Description

N-methylation of endogenous and xenobiotic compounds is a major method by which they are degraded. This gene encodes an enzyme that N-methylates indoles such as tryptamine. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream FAM188B (family with sequence similarity 188, member B) gene.

Pathway

Selenocompound metabolism; Tryptophan metabolism; nicotine degradation IV;