Recombinant fragment within Human ING2. The exact sequence is proprietary.Database link: Q9H160
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/1000 - 1/5000;
Target
Alternative Names
ING2; inhibitor of growth family, member 2; ING1L, inhibitor of growth family, member 1 like; inhibitor of growth protein 2; p33ING2; p32; ING1Lp; inhibitor of growth 1-like protein; ING1L;
Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).
Pathway
Senescence and Autophagy, organism-specific biosystem;
Citations
Publication ()
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COA
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