Anti-ING1 (aa 285-296) polyclonal antibody

Species Reactivity

Human; Mouse

Immunogen

A synthetic peptide corresponding to amino acids 285-296 of human ING1.

Conjugate

Application Notes

ELISA: 1:4000-1:14000; WB: 1:500-1:3000. & The optimal working dilution should be determined by the end user.

Alternative Names

ING1; inhibitor of growth family, member 1; p33; p47; p33ING1; p24ING1c; p33ING1b; p47ING1a; inhibitor of growth protein 1; growth inhibitor ING1; tumor suppressor ING1; growth inhibitory protein ING1;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.

Pathway

Senescence and Autophagy.