Specifications
Applications
Application Notes
WB: 1:1,000 - 10,000 (10 ng)
Target
Alternative Names
IL28B; interleukin 28B (interferon, lambda 3); interleukin 28B; interleukin-28B; IFNL3; IL 28B; IL28C; IL-28C; IFN-lambda-3; IFN-lambda-4; interleukin 28C; interleukin-28C; cytokine Zcyto22; interferon lambda-3; interferon lambda-4; interferon, lambda 3;
Product Background
Antigen Description
IL-28 is a cytokine distantly related to type I interferons and the IL-10 family. Interleukin 28A (IL-28A), and interleukin 29 (IL-29) are three closely related cytokine proteins. Expression of the cytokines can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin20receptor, beta (IL-10RB) and interleukin 28 receptor, alpha (IL-28RA).
Pathway
Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Citations
Publication ()
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