Rabbit anti-Mouse IL23 Receptor polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant full length protein corresponding to Human IL23 Receptor.

Conjugate

Alternative Names

IL23R; interleukin 23 receptor; IL-23R; interleukin-23 receptor; IL-23 receptor;

Entrez Gene ID

UniProt ID

Antigen Description

Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.

Pathway

Cytokine-cytokine receptor interaction; Inflammatory bowel disease (IBD); Jak-STAT signaling pathway;