Specifications
Immunogen
A synthetic peptide of human IGSF5 is used for rabbit immunization.
Target
Alternative Names
IGSF5; immunoglobulin superfamily, member 5; immunoglobulin superfamily member 5; JAM4; junctional adhesion molecule 4; JAM-4; immunoglobulin superfamily 5 like; GSF5;
Product Background
Antigen Description
Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells.
Pathway
Epithelial cell signaling in Helicobacter pylori infection, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, conserved biosystem; Tight junction, organism-specific biosystem; Tight junction, conserved biosystem.
Citations
Publication ()
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COA
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