Anti-IgG3 polyclonal antibody [HRP] (CPBT-65546SH)

Sheep anti-Human IgG3 polyclonal antibody for IHC-Fr, ELISA. Datasheet

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Specifications


Host Species
Sheep
Antibody Isotype
Polyclonal IgG
Species Reactivity
Human
Immunogen
Human IgG3 (kappa & lambda) purified from human myeloma serum.
Conjugate
HRP

Target


Alternative Names
IGHG3; immunoglobulin heavy constant gamma 3 (G3m marker); IgG3; ; immunoglobulin heavy constant gamma 3
Entrez Gene ID
UniProt ID
P01860

Product Background


Pathway
Classical antibody-mediated complement activation; Complement cascade; Creation of C4 and C2 activators; FCGR activation; Fcgamma receptor (FCGR) dependent phagocytosis; IL4-mediated signaling events; Immune System; Initial triggering of complement;

Citations


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References


Elluru, R; Kaveri, SV; et al. The protective role of immunoglobulins in fungal infections and inflammation. SEMINARS IN IMMUNOPATHOLOGY 37:187-197(2015).
Shao, YY; Fu, R; et al. IgG autoantibody subclasses altered in immuno-related hemocytopenia. CELLULAR IMMUNOLOGY 294:13-20(2015).

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