Anti-IgG3 polyclonal antibody [HRP] (CPBT-65546SH)

Sheep anti-Human IgG3 polyclonal antibody for IHC-Fr, ELISA. Datasheet

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Specifications


Host Species
Sheep
Antibody Isotype
Polyclonal IgG
Species Reactivity
Human
Immunogen
Human IgG3 (kappa & lambda) purified from human myeloma serum.
Conjugate
HRP

Target


Alternative Names
IGHG3; immunoglobulin heavy constant gamma 3 (G3m marker); IgG3; ; immunoglobulin heavy constant gamma 3
Entrez Gene ID
UniProt ID
P01860

Product Background


Pathway
Classical antibody-mediated complement activation; Complement cascade; Creation of C4 and C2 activators; FCGR activation; Fcgamma receptor (FCGR) dependent phagocytosis; IL4-mediated signaling events; Immune System; Initial triggering of complement;

Citations


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References


Tan, JF; Jin, XF; et al. Beneficial effect of T follicular helper cells on antibody class switching of B cells in prostate cancer. ONCOLOGY REPORTS 33:1512-1518(2015).
Mckay, JT; Egan, RP; et al. PD-1 Suppresses Protective Immunity to Streptococcus pneumoniae through a B Cell-Intrinsic Mechanism. JOURNAL OF IMMUNOLOGY 194:2289-2299(2015).

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