Rabbit Anti-Human IFT80 (a.a. 417-777) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Recombinant human IFT80 protein; Source: E. coli derived, PET28a; Tag: 6*His; Domain: 417-777 aa of BC101494

Conjugate

Application Notes

WB: 1:1000-1:8000

General Notes

This product (Catalog No. DPABH-22926) is a rabbit-derived polyclonal antibody raised against human IFT80, targeting the amino acid region 417–777 of the protein. This antibody exhibits cross-reactivity with Human IFT80 from mouse. It has been affinity purified by Protein A. IFT80 is an intraflagellar transport (IFT) protein that plays a crucial role in the formation and function of primary cilia. IFT proteins are key for cilia formation, and it seems that this organelle has developed into a complex signaling center in mammals, providing important sensory functions. IFT80 is a recently-defined component of IFT complex B, and loss of IFT80 in zebrafish results in cystic kidneys and a reduced number of cilia, whereas silencing IFT80 in Tetrahymena thermophila produces shortened or absent cilia. (PMID: 23333501).
DPABH-22926 is suitable for use in Western blot (WB) (1:1,000–1:8,000) application.
DPABH-22926 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

ATD2; IFT; KIAA1374; WD repeat-containing protein 56; WDR56

Entrez Gene ID

UniProt ID