Anti-IFITM1 (N-terminal) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide corresponding to a sequence at the N terminus of Human IFITM1, identical to the related Rat and Mouse sequence.

Conjugate

Application Notes

WB: 1 μg/ml; IHC-P: 0.5 - 1 μg/ml.

Alternative Names

IFITM1; interferon induced transmembrane protein 1; IFI17, interferon induced transmembrane protein 1 (9 27); interferon-induced transmembrane protein 1; 9 27; CD225; leu-13 antigen; interferon-induced protein 17; interferon-inducible protein 9-27; 9-27;

Entrez Gene ID

UniProt ID

Antigen Description

IFN-induced antiviral protein that mediate cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus, and dengue virus by inhibiting the early step(s) of replication. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activition or by arresting cell growth in G1 phase in a p53-dependent manner. Implicated in the control of cell growth. Component of a multimeric complex involved in the transduction of antiproliferative and homotypic adhesion signals.

Pathway

Adaptive Immune System; B cell receptor signaling pathway; Cytokine Signaling in Immune system; Immune System; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell; Interferon Signaling;