Anti-VIPR1 monoclonal antibody, clone BT69

Antibody Isotype

IgG2a

Clone

BT69

Species Reactivity

Rat; Human

Immunogen

Recombinant full length protein (Human).

Conjugate

Application Notes

WB: 1 - 10μg/ml; Flow Cyt: 0.5 - 1μg/ml;

Alternative Names

VIPR1; vasoactive intestinal peptide receptor 1; vasoactive intestinal polypeptide receptor 1; HVR1; RDC1; VIP and PACAP receptor 1; VPAC1; VPAC1R; FLJ41949; HVR 1; HVR1; II; PACAP R 2; PACAP type II receptor; PACAP-R-2; PACAP-R2; Pituitary adenylate cycl

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene.

Pathway

Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Glucagon-type ligand receptors, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neu