Anti-PLIN3 (aa 1-16) polyclonal antibody

Species Reactivity

Human

Immunogen

Synthetic peptide of TIP47 N-terminus (aa 1 – 16)

Conjugate

Application Notes

1:100 - 200 for immunohistochemistry; 1:1000 for immunoblotting (Western (ECL))

Alternative Names

PLIN3; perilipin 3; PP17; TIP47; M6PRBP1; mannose-6-phosphate receptor binding protein 1; cargo selection protein (mannose 6 phosphate receptor binding protein); MPR-BINDING PROTEIN, 47-KD; placental protein 17; Perilipin-3; 47 kDa mannose 6-phosphate rec

Entrez Gene ID

UniProt ID

Antigen Description

Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.