Anti-ROR1 monoclonal antibody (CABT-34798MH)

Mouse anti-Human ROR1 monoclonal antibody for ELISA, ICC/IF, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
3I7
Species Reactivity
Human
Immunogen
Recombinant fragment, corresponding to extracellular amino acids 30-406 of Human ROR1 fused with hIgGFc tag, expressed in HEK293 cells.
Conjugate
Unconjugated

Applications


Application Notes
Flow Cyt: 2μg/106 cells; WB: 1/500 - 1/2000; ELISA: 1/10000; ICC/IF: 1/200 - 1/1000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ROR1; receptor tyrosine kinase-like orphan receptor 1; NTRKR1; tyrosine-protein kinase transmembrane receptor ROR1; dJ537F10.1; receptor-related 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Nuclear Receptors, organism-specific biosystem;

Citations


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References


Hudecek, M; Lupo-Stanghellini, MT; et al. Receptor Affinity and Extracellular Domain Modifications Affect Tumor Recognition by ROR1-Specific Chimeric Antigen Receptor T Cells. CLINICAL CANCER RESEARCH 19:3153-3164(2013).
Fukuda, T; Chen, L; et al. Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal,antigen and receptor for Wnt5a. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105:3047-3052(2008).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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