Anti-ROR1 monoclonal antibody (CABT-34798MH)
Mouse anti-Human ROR1 monoclonal antibody for ELISA, ICC/IF, WB
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Recombinant fragment, corresponding to extracellular amino acids 30-406 of Human ROR1 fused with hIgGFc tag, expressed in HEK293 cells.
Flow Cyt: 2μg/106 cells; WB: 1/500 - 1/2000; ELISA: 1/10000; ICC/IF: 1/200 - 1/1000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
ROR1; receptor tyrosine kinase-like orphan receptor 1; NTRKR1; tyrosine-protein kinase transmembrane receptor ROR1; dJ537F10.1; receptor-related 1
Nuclear Receptors, organism-specific biosystem;
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Hudecek, M; Schmitt, TM; et al. The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor. BLOOD 116:4532-4541(2010).
Daneshmanesh, AH; Hojjat-Farsangi, M; et al. ANTI-ROR1 MONOCLONAL ANTIBODIES INDUCED APOPTOSIS OF CLL CELLS AND ALTERED PHOSPHORYLATION OF SRC AND PI3-KINASES. HAEMATOLOGICA 99:51-52(2014).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.