Pituitary adenylate cyclase-activating polypeptide also known as PACAP is a protein that in humans is encoded by the ADCYAP1 gene. PACAP is similar to vasoactive intestinal peptide. One of its effects is to stimulate enterochromaffin-like cells. It binds to vasoactive intestinal peptide receptor.
Pathway
Activation of TRKA receptors; Class B/2 (Secretin family receptors); GPCR downstream signaling; GPCR ligand binding; NGF signalling via TRKA from the plasma membrane; SIDS Susceptibility Pathways; Signaling by GPCR; Signalling by NGF
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