Rabbit Anti-Human POLG2 (internal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from internal of human POLG2.

Conjugate

Application Notes

IHC: 1:50-1:100

General Notes

This product (Catalog No. CPBT-43694RH) is a rabbit-derived IgG polyclonal antibody raised against human POLG2. This antibody exhibits cross-reactivity with POLG2 from mouse. It has been affinity purified by protein A. This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
CPBT-43694RH is suitable for use in IHC (1:50–1:100) application.
CPBT-43694RH is supplied as a liquid formulation in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

DNA polymerase subunit gamma-2; mitochondrial; EC 2.7.7.7; Mitochondrial DNA polymerase accessory subunit; PolG-beta

Entrez Gene ID

UniProt ID