Rabbit Anti-Human G6PC (a.a. 1-62) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Rat

Immunogen

Recombinant human G6PC protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 1-62 aa of BC136369

Conjugate

Application Notes

WB: 1:1000-1:6000

General Notes

This product (Catalog No. CPBT-35447RH) is a rabbit-derived polyclonal antibody raised against human G6PC, targeting the amino acid region 1–62 of the protein. This antibody exhibits cross-reactivity with Human G6PC from rat. It has been affinity purified by Protein A. Glucose-6-phosphatase-α (G6PC) is a key enzyme in glucose homeostasis that catalyzes the hydrolysis of glucose-6-phosphate to glucose and phosphate in the terminal step of gluconeogenesis and glycogenolysis. G6PC activity is restricted to the liver, the kidney cortex, and the small intestine and confers on these three organs the capacity to release glucose into the systemic circulation (PMID: 21983240). The encoded enzyme is anchored to the ER by nine transmembrane helices with the amino (N)-terminus in the lumen and the carboxyl (C)-terminus in the cytoplasm (PMID: 15542400).
CPBT-35447RH is suitable for use in Western blot (WB) (1:1,000–1:6,000) application.
CPBT-35447RH is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

G6PC1; G6PT; G6Pase-alpha; G-6-Pase; G6Pase

Entrez Gene ID

UniProt ID