Anti-FN monoclonal antibody (DMAB1528MH)
Mouse anti-Human ITGB5 monoclonal antibody for EIA, WB
Bring this labeled antibody directly to your bench!
Online Inquiry Add to basket
Human plasma fibronectin
FN; CIG; FNZ; MSF; ED-B; FINC
Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins. In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin and heparan sulfate proteoglycans (e. g. syndecans). Fibronectin exists as a dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms. The function about FN antigen include Collagen binding; extracellular matrix structural constituent; heparin binding; protein binding.
Amoebiasis, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem.
Have you cited DMAB1528MH in a publication? Let us know
and earn a reward for your research.
Su, J; Yin, LP; et al. Chronic Allograft Nephropathy in Rats Is Improved by the Intervention of Rhein. TRANSPLANTATION PROCEEDINGS 45:2546-2552(2013).
Kong, M; Munoz, N; et al. Thy-1-mediated cell-cell contact induces astrocyte migration through the engagement of alpha v beta(3) integrin and syndecan-4. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1833:1409-1420(2013).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.