Anti-FN monoclonal antibody (DMAB1528MH)
Mouse anti-Human ITGB5 monoclonal antibody for EIA, WB
Bring this labeled antibody directly to your bench!
Online Inquiry Add to basket
Human plasma fibronectin
FN; CIG; FNZ; MSF; ED-B; FINC
Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins. In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin and heparan sulfate proteoglycans (e. g. syndecans). Fibronectin exists as a dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms. The function about FN antigen include Collagen binding; extracellular matrix structural constituent; heparin binding; protein binding.
Amoebiasis, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Bacterial invasion of epithelial cells, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem.
Have you cited DMAB1528MH in a publication? Let us know
and earn a reward for your research.
Sakkas, LI; Bogdanos, DP; et al. Anti-citrullinated peptides as autoantigens in rheumatoid arthritis-relevance to treatment. AUTOIMMUNITY REVIEWS 13:1114-1120(2014).
Sullivan, MA; Wentworth, T; et al. Anti-idiotypic monobodies for immune response profiling. METHODS 58:62-68(2012).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.