General Notes
This product (Catalog No. CPBT-53181RH) is a rabbit-derived polyclonal antibody raised against human ESRRG, targeting the amino acid region 94–442 of the protein. This antibody exhibits cross-reactivity with Human ESRRG from mouse and rat. It has been affinity purified by Protein A. Estrogen-related receptor gamma (ERR-gamma), also known as NR3B3 (nuclear receptor subfamily 3, group B, member 3), is a member of nuclear hormone receptor family of steroid hormone receptors. As an orphan nuclear receptor, it binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements. It behaves as a constitutive activator of transcription. 4-hydroxytamoxifen and diethylstilbestrol may act as inverse agonists and deactivate ESRRG. It also seems to be the target of bisphenol A.
CPBT-53181RH is suitable for use in Western blot (WB) (1:1,000–1:4,000), IHC (1:2,000–1:8,000) applications.
CPBT-53181RH is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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