Anti-E2F1 monoclonal antibody (DMAB5487MH)

Mouse anti-Human E2F1 monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
JG96
Species Reactivity
Human
Immunogen
BALB/C mice were immunized with a recombinant Human E2F-1 protein.
Conjugate
Unconjugated

Target


Alternative Names
E2F1; E2F1 E2F transcription factor 1; RBP3; E2F-1; RBAP1; RBBP3
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of BH3-only proteins; Activation of NOXA and translocation to mitochondria; Activation of PUMA and translocation to mitochondria; Adipogenesis; Apoptosis; Assembly of the pre-replicative complex; Association of licensing factors with the pre-re

Citations


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References


Jordan-Sciutto, KL; Wang, GJ; et al. Induction of cell-cycle regulators in simian immunodeficiency virus encephalitis. AMERICAN JOURNAL OF PATHOLOGY 157:497-507(2000).
Lu, Z; Luo, RZ; et al. E2F-HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer. ONCOGENE 25:230-239(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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