Anti-CDK2 monoclonal antibody (DMAB5466MH)

Mouse anti-Human CDK2 monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
3C7
Species Reactivity
Human
Immunogen
BALB/C mice were injected with a human recombinant cdk2 protein.
Conjugate
Unconjugated

Target


Alternative Names
CDK2; p33(CDK2); cyclin-dependent kinase 2; p33 protein kinase; cell devision kinase 2; cdc2-related protein kinase
Entrez Gene ID
UniProt ID

Product Background


Pathway
APC/C-mediated degradation of cell cycle proteins; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; B Cell Receptor Signaling Pathway; BARD1 signaling events; CDK-mediated phosphorylation and removal of Cdc6;

Citations


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References


Bao, WJ; Thullberg, M; et al. Cell attachment to the extracellular matrix induces proteasomal degradation of p21(CIP1) via Cdc42/Rac1 signaling. MOLECULAR AND CELLULAR BIOLOGY 22:4587-4597(2002).
Bacus, SS; Yarden, Y; et al. Neu differentiation factor (Heregulin) activates a p53-dependent pathway in cancer cells. ONCOGENE 12:2535-2547(1996).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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