Anti-CXCR1 monoclonal antibody (CABT-29133MH)

Mouse anti-Human CXCR1 monoclonal antibody for FC, IHC-Fr, Inhib Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
53806.222
Species Reactivity
Mouse, Human
Immunogen
Human CXCR1 transfected NSO mouse myeloma cells.
Conjugate
Unconjugated

Applications


Application Notes
IHC-Fr: 25 μg/ml; Flow Cyt: 10μl/105-106 cells; Inhibition Assay : 0.1 - 0.3 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CXCR1; chemokine (C-X-C motif) receptor 1; CMKAR1, IL8RA,interleukin 8 receptor, alpha; C-X-C chemokine receptor type 1; CD181; CDw128a
Entrez Gene ID
UniProt ID

Product Background


Pathway
Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Epithelial cell signaling in Helicobacter pylori infe

Citations


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References


Okada, Y; Meguro, M; et al. Human leukocyte histocompatibility antigen class II-induced cytokines from human gingival fibroblasts promote proliferation of human umbilical vein endothelial cells: potential association with enhanced angiogenesis in chronic periodontal inflammation. JOURNAL OF PERIODONTAL RESEARCH 44:103-109(2009).
Heidemann, J; Ogawa, H; et al. Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2. JOURNAL OF BIOLOGICAL CHEMISTRY 278:8508-8515(2003).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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