Anti-BCL2L1 monoclonal antibody (DMAB5401MH)

Mouse anti-Human BCL2L1 monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
3I13
Species Reactivity
Human
Immunogen
BALB/C mice were injected with a synthetic peptide of amino acid 3-14 (Cys-QSNRELVVDFLS) of human bcl-X protein.
Conjugate
Unconjugated

Target


Alternative Names
BCL2L1; BCL2-like 1; BCLX; BCL2L; BCLXL; BCLXS
Entrez Gene ID
UniProt ID

Product Background


Pathway
Amyotrophic lateral sclerosis (ALS); Apoptosis; BH3-only proteins associate with and inactivate; anti-apoptotic BCL-2 members; Chronic myeloid leukemia; EPO signaling pathway; HTLV-I infection; IL-3 Signaling Pathway; IL-4 signaling Pathway; IL2 signaling

Citations


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References


Vikstrom, I; Carotta, S; et al. Mcl-1 Is Essential for Germinal Center Formation and B Cell Memory. SCIENCE 330:1095-1099(2010).
Willimott, S; Wagner, SD; et al. miR-125b and miR-155 Contribute to BCL2 Repression and Proliferation in Response to CD40 Ligand (CD154) in Human Leukemic B-cells. JOURNAL OF BIOLOGICAL CHEMISTRY 287:2608-2617(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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